Amine-based plasma polymer thin films (NH2-PPTFs) are favorable due to their potential ability for binding a variety of biomolecules, especially in biotechnologic studies. In this context, to understand the effect of different amine sources on quartz tuning forks’ (QTF) surface functionalization and isolation, we prepared PPTFs by single-step plasma polymerization process. The amino-group concentration of PPTF's was proportionally increased by increasing discharge powers, whereas not affected from exposure time. It was observed that the resistivity increased with the increasing molecular weight of the precursor. In conclusion, NH2-PPTF-modified QTFs present as a great candidate for future biotechnologic applications.